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Peter L J Wijngaard Selected Research

MDCO-216

12/2016Persistent changes in lipoprotein lipids after a single infusion of ascending doses of MDCO-216 (apoA-IMilano/POPC) in healthy volunteers and stable coronary artery disease patients.
4/2016High-Density Lipoprotein Subfractions and Cholesterol Efflux Capacities After Infusion of MDCO-216 (Apolipoprotein A-IMilano/Palmitoyl-Oleoyl-Phosphatidylcholine) in Healthy Volunteers and Stable Coronary Artery Disease Patients.
1/2014Incubation of MDCO-216 (ApoA-IMilano/POPC) with Human Serum Potentiates ABCA1-Mediated Cholesterol Efflux Capacity, Generates New Prebeta-1 HDL, and Causes an Increase in HDL Size.

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Peter L J Wijngaard Research Topics

Disease

4Cardiovascular Diseases (Cardiovascular Disease)
01/2021 - 01/2019
2Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
01/2021 - 01/2020
2Coronary Artery Disease (Coronary Atherosclerosis)
12/2016 - 04/2016
1Atherosclerosis
01/2021
1Homozygous Familial Hypercholesterolemia
01/2020
1Dyslipidemias (Dyslipidemia)
01/2019
1Stable Angina
04/2016
1Atherosclerotic Plaque (Atheroma)
01/2014

Drug/Important Bio-Agent (IBA)

5LDL CholesterolIBA
01/2021 - 01/2019
4ALN-PCSIBA
01/2021 - 01/2019
3MDCO-216IBA
12/2016 - 01/2014
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2021 - 01/2020
2oxidized low density lipoproteinIBA
01/2021 - 01/2019
2Small Interfering RNA (siRNA)IBA
01/2020 - 01/2019
2Apolipoproteins AIBA
12/2016 - 01/2014
2Phosphatidylcholines (Phosphatidylcholine)IBA
04/2016 - 01/2014
1LDL Lipoproteins (beta Lipoproteins)IBA
01/2020
1SodiumIBA
01/2020
1Proprotein Convertase 9IBA
01/2020
1Lipoproteins (Lipoprotein)IBA
12/2016
1LipidsIBA
12/2016
1CholesterolIBA
04/2016
1HDL LipoproteinsIBA
04/2016
1Apoprotein(a) (Apolipoprotein (a))IBA
04/2016

Therapy/Procedure

3Therapeutics
01/2021 - 01/2019
2Subcutaneous Injections
01/2021 - 01/2020